Now Foods. ALCAR
Acetyl L-Carnitine is used to treat mitochondrial aging when given with alpha lipoic acid. It makes old rats behave like young ones. Acetyl L-Carnitine with alpha lipoic acid rejuvenates aging mitochondria and appears to solve most problems posed by mitochondrial factors in aging. Pre-treatment of monkeys with acetyl-L-carnitine prevents artificially induced Parkinson's Disease. Acetyl L-carnitine was developed by scientists as a more bioavailable form of L-carnitine and must be taken as a supplement.
Acetyl L-Carnitine has been reported as elevating Nerve Growth Factor (NGF) by as much as 100 times. Nerve Growth Factor promotes Id-1 helix-loop-helix transcription factor protein, which can activate telomerase expression and inhibit transcription of the tumor suppressor protein p16INK4a (Zheng et al. 2004, Ohani et al. 2001), which can accumulate until it induces cellular senescence and inhibits neural forebrain progenitors, reducing neurogenesis.
